False Discovery Control in Large-Scale Spatial Multiple Testing.

The False Discovery Rate in Simultaneous Fisher and Adjusted Permutation Hypothesis Testing on Microarray Data

Background and Objectives: In recent years, new technologies have led to produce a large amount of data and in the field of biology, microarray technology has also dramatically developed. Meanwhile, the Fisher test is used to compare the control group with two or more experimental groups and also to detect the differentially expressed genes. In this study, the false discovery rate was investiga...

Web Appendix for “False Discovery Control in Large- Scale Spatial Multiple Testing”

Global Testing and Large-Scale Multiple Testing for High-Dimensional Covariance Structures

Driven by a wide range of contemporary applications, statistical inference for covariance structures has been an active area of current research in high-dimensional statistics. This paper provides a selective survey of some recent developments in hypothesis testing for high-dimensional covariance structures, including global testing for the overall pattern of the covariance structures and simul...

Wavelet shrinkage versus Gaussian spatial filtering of functional MRI data

Objective The comparison between wavelet-based simultaneous multiscale denoising/hypothesis testing and single scale Gaussian spatial filtering followed by statistical testing of brain activation maps is carried out for a simple block-type visual paradigm EPI MRI experiment. Probabilistic wavelet shrinkage provides means to consistently combine multiresolution denoising and hypothesis testing i...

Optimal detection of functional connectivity from high-dimensional EEG synchrony data

Computing phase-locking values between EEG signals is a popular method for quantifying functional connectivity. However, this method involves large-scale, high-resolution datasets, which impose a serious multiple testing problem. Standard multiple testing methods fail to exploit the information from the complex dependence structure that varies across hypotheses in spectral, temporal, and spatia...